1. Basic information
Name: amino-polyethylene glycol hydroxyl; Alpha-amino-ω-hydroxyl polyethylene glycol
Abbreviation: H2N-PEG-OH or Amine-PEG-OH
Molecular weight: PEG has a variety of molecular weight, such as 2000, 3400, 5000, etc., the specific molecular weight can be customized according to demand.
2. Physical properties
Appearance: Depending on the molecular weight, H2N-PEG-OH may appear as a white/white solid or a viscous liquid.
Solvent: Soluble in dichloromethane, DMSO, water and other conventional organic solvents.
Storage conditions: It is recommended to store the storage in a -20°C environment away from light and humidity.
3. Chemical properties
Functional groups: The H2N-PEG-OH molecule contains two functional groups: amino (-NH2) and hydroxyl (-OH). Amino group is nucleophilic and can participate in many chemical reactions, such as nucleophilic substitution, nucleophilic addition, etc. The hydroxyl group is a polar group with hydrophilic and hydrogen bond forming ability.
Reactivity: H2N-PEG-OH can be chemically modified to introduce different functional groups at one or both ends of the PEG chain to meet specific application needs. For example, it can amidate molecules with carboxylic groups (COOH) or other electrophilic groups to form stable covalent bonds.
4. Application
Research use: H2N-PEG-OH is widely used in scientific research because of its good water solubility and biocompatibility. It can be used as a crosslinking agent, catalyst or reactant to participate in chemical reactions. It can also be combined with biomolecules or cells to form stable complexes for the separation and purification of biomolecules or cells.
Note: H2N-PEG-OH is for scientific use only, not for human experiments. During use and storage, attention should be paid to maintaining its stability and avoiding contamination.
Related recommendations:
Name
Abbreviation
CAS#
α-Amino-ω-hydroxyl poly(ethylene glycol)
H2N-PEG-OH
32130-27-1
α-Amino-ω-mercapto poly(ethylene glycol)
H2N-PEG-SH
α-Carboxyl-ω-hydroxyl poly(ethylene glycol)
HOOC-PEG-OH
α-Propionyloxy-ω-azido poly(ethylene glycol)
PA-PEG-N3
1214319-92-2
α-Carboxyl-ω-glycidyl poly(ethylene glycol)
HOOC-PEG-EO
α-Acryloyl-ω-carboxyl poly(ethylene glycol)
AA-PEG-COOH
α-Formyl-ω-hydroxyl poly(ethylene glycol)
OHC-PEG-OH
α-Formyl-ω-azido poly(ethylene glycol)
OHC-PEG-N3
α-Acetal-ω-amino poly(ethylene glycol)
Acetal-PEG-NH2
α-Maleimidyl-ω-hydroxyl poly(ethylene glycol)
MAL-PEG-OH
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