Lipid nanoparticle (LNP) delivery systems are widely used in the fields of gene therapy and vaccines.However, to achieve effective gene delivery and vaccine delivery, not only suitable carriers and nucleic acids or antigens need to be selected, but also excipients for LNP delivery systems are needed.These excipients play a key role in stability, transparency, protective effect, and charge capacity. Firstly, stability is an important characteristic of excipients for LNP delivery systems.Excipients interact with lipid components, increasing the stability of LNP.For example, polyethylene glycol (PEG) is one of the commonly used excipients, which can form a stable layer of polymer by covering the surface of LNP.This polymer layer helps to reduce protein and cell adsorption and provides additional stability, thereby prolonging the circulation life of LNP. Secondly, transparency is an important factor to be considered when designing LNP delivery systems.Transparency can affect the preparation of LNP and the visualization of the internal structure.Therefore, excipients are usually selected for their characteristics of lower absorption and scattering of light to obtain clear imaging and accurate structural analysis. In addition, excipients for LNP delivery systems can also provide protection, protecting nucleic acids or antigens from degradation. For example, cholesterol is a common excipient that can be inserted into LNP to form a barrier that protects the nucleic acid or antigen.This protective layer can prevent the nucleic acid or antigen from being attacked by enzymes and help improve delivery efficiency and immune activation. In addition, charge is also an important characteristic of excipients.Charge can affect the interaction between LNP and target cells and delivery efficiency.For example, some excipients can regulate the charge state on the surface of LNP to improve its adsorption and cell uptake, thus improving delivery effect. In summary, excipients in LNP delivery systems play an important role in gene therapy and vaccine research.By selecting appropriate excipients, the stability, transparency, protective effect and charge of LNP can be optimized to achieve efficient gene delivery and vaccine delivery.Researchers will continue to develop new excipients to further improve the performance of LNP delivery systems and promote the development of gene therapy and vaccine research. Lipids that has been registered with DMF: DLin-MC3-DMA* SM-102 (HUO)* ALC-0315 (DHA)* DHA-1 (ALC-0315 analogue) mPEG-DMG-2K ALC-0159 (mPEG-DTA)* mPEG-DTA-1-2K (ALC-0159 analogue) DSPC DOPE DOTAP-Cl Cholesterol (Plant) Click here for more lipid products * This product is protected by third-party patents. We provide patent-compliant technical consultation and services, not the product itself.

We are delighted to announce that SINOPEG will be participating in the LNP Formulation & Process Development Summit 2024 Agreement, scheduled to take place on April 29, 2024, in Boston, USA. This prestigious exhibition offers a unique platform for industry professionals to gather and exchange valuable insights on the latest advancements in LNP formulation and process development. We extend a warm welcome to everyone interested in this field to join us at this exciting event. Powered by latest developments with LNP CRISPR gene editing in the lungs, Bayer and Acuitas uniting to strengthen their Gene Therapy portfolio, new biotech ReNAgade Therapeutics launching with $300m Series A financing, lipid nanoparticles continue to dominate biopharma pipelines in 2024 and beyond as the most successful non-viral delivery vehicle to date. Moving into novel applications from gene therapy and cell therapy, and new disease indications from oncology to rare disease, LNP are equipping scientists with the ability to deliver transformative medicines to patients. With industry at a critical inflection point as a need to demonstrate clinical advancements for confidence to advance pipelines in 2024, the 3rd LNP Formulation & Process Development Summit will unite again in April with 4 tracks of carefully curated content as the industry’s one-stop-shop to evaluate and optimize LNPs end-to-end development for your given target of interest. *60+ expert speakers pioneering the next generation of LNP drug products *Content from early-stage discovery through the commercialized manufacture at large scale *A plethora of payloads, disease indications and route of administration *8 in-depth workshops, LNP 101 focus day, IP Patenting & Commercial Partnerships focus day, and 10+ hours of dedicated networking *Countless new topics, new speakers and new companies Date: April 29, 2024 Location:Boston, USA For more information and registration details, please visit the official website of the LNP Formulation & Process Development Summit 2024 Agreement. The LNP Formulation & Process Development Summit 2024 Agreement in Boston is an event not to be missed for professionals in the field of LNP formulation and process development.  We look forward to welcoming you to this exciting exhibition, where we can collectively contribute to the advancement of this rapidly evolving field. See you there!

Happy New Year! Wishing you all a year filled with joy, success, and endless possibilities. May this new year bring you happiness and fulfillment in everything you do. Let's embrace new beginnings and make the most of every moment. Cheers to a fantastic year ahead! #NewYear #2024

Dear colleagues and industry partners, We are thrilled to extend a warm invitation to all of you to join us at CPHI Barcelona 2023, one of the most prestigious events in the pharmaceutical and healthcare industry. Our company is proud to be a part of this incredible event, and we're excited to welcome you to our booth, 7D10. Event Details: Date: 24 Oct, 2023–26 Oct, 2023 Location: Fira Barcelona Gran Via Booth: 7D10 At our booth, you'll have the opportunity to connect with our team, explore our latest products and innovations, and engage in meaningful discussions about the future of the pharmaceutical industry. CPHI Barcelona is a hub for networking and knowledge-sharing, and we look forward to exchanging insights with you. Why Visit Booth 7D10? Discover our cutting-edge pharmaceutical solutions. Learn about our commitment to quality and innovation. Meet our team of experts ready to answer your questions. Explore potential collaborations and partnerships. To make the most of your visit, please schedule an appointment with us in advance by contactingsales@sinopeg.com. We believe that collaboration is key to driving the industry forward, and CPHI Barcelona provides the perfect platform for such collaboration.     We can't wait to see you there and discuss how we can work together to achieve excellence in the world of pharmaceuticals. Save the date, visit Booth 7D10, and let's shape the future of healthcare together!

The 2nd LNP Formulation & Process Development Summit is returning to Boston to welcome 350+ LNP experts for sharing, learning and networking to turbocharge next generation of LNP development. Welcome to visit SINOPEG at booth no.27. 2nd LNP Formulation & Process Development Summit | April 2023 (lnp-formulation-process-development-pharma.com) #event #Boston Xiamen Sinopeg Biotech Co., Ltd. is dedicated to drug delivery systems and related medical device business, focusing on the research, development, production and sales of high-end drug delivery carriers/auxiliary materials/APIs, medical materials, including but not limited to polyethylene glycol derivatives, lipid products, blood sugar control drug modifiers, block copolymers, ADC/ProTAC linkers, biodegradable polymers, exosomes, viral-like particles, as well as providing CDMO and solution services. These products are widely used in long-acting protein/peptide drugs, COVID-19 mRNA vaccines, small nucleic acid drugs, blood sugar control drugs, macromolecular micelle drugs, liposome drugs, gene therapy drugs, immunosuppressants, ADC drugs, ProTAC drugs, medical hydrogels, and other fields, placing the company in a leading position in the industry.

Cell & Gene Therapy Bioprocessing & Commercialization is the most focused event for cost effective and efficient cell, gene and immunotherapy approaches. CGT delivers the focused science and business content designed specifically for the cell therapy and regenerative medicine fields, while providing a pivotal gathering place for connecting industry, funding sources, government and academia. Welcome to visit us at SINOPEG's Booth#104at CGT, Boston Convention and Exhibition Center, USA from 27th to 30th September. https://informaconnect.com/cell-therapy-bioprocessing/ #event #CGT #Boston SINOPEG is a dynamic science company with professional R&D, Manufacturing and Sales capability. The company is mainly engaged in drug delivery system (DDS) and new medical materials business. Founded in 2011, SINOPEG has a team of highly qualified and science background employee personnel. We devote ourselves to research, develop and produce high quality Polyethylene glycol, Polyethylene glycol derivatives, Block copolymers, Anti-diabetic drug side chains, lipids for LNPs, GalNAc conjugates, ADC and ProTAC Linker, etc. Please contact us at sales@sinopeg.com 

Welcome to visit us at SINOPEG's Booth #2351 at BIO International Convention 2022, San Diego, USA from 13th to 16th June. SINOPEG is mainly engaged in drug delivery system (DDS) and new medical materials business. SINOPEG has a high-level team with strong technical reserve to research, develop and produce high-quality polyethylene glycol, polyethylene glycol derivatives, block copolymers, anti-diabetic drug side chains, lipid excipients (ingredients for mRNA delivery system), ADC and ProTAC Linker, etc. Please contact us at sales@sinopeg.com #BIO

Welcome to visit us at SINOPEG's Booth #137 at Tides USA 2022, Boston, USA from 9th to 12th May. SINOPEG has a high-level team with strong technical reserve to research, develop and produce high-quality polyethylene glycol, polyethylene glycol derivatives, block copolymers, anti-diabetic drug side chains, lipid excipients (ingredients for mRNA delivery system), ADC and ProTAC Linker, etc. Please coutact us at sales@sinopeg.com