Name: Methoxypoly(ethylene glycol) amine

Product Abbreviation: mPEG-NH2

Molecular Weight: 2K, 5K, 10K, 20K, 40K

Packaging Sizes: 1g, 5g, 10g, 100g, 1kg, 10kg

Storage: -20±5℃

Physical Form: Granular Solid

Color: White to Off-White

1. Structure and Properties Structure: mPEG-NH2 comprises two components, mPEG (methoxypolyethylene glycol) and NH2 (amine). The mPEG segment is a linear or branched polymer composed of repeating ethylene glycol units, terminated with a methoxy group, providing mPEG-NH2 with good water solubility and biocompatibility. The NH2 segment is an amino group, imparting reactivity and functionality to mPEG-NH2. Properties: Water Solubility: mPEG-NH2 exhibits excellent water solubility, dispersing well in water to form transparent solutions. Biocompatibility: Due to its biocompatibility, mPEG-NH2 finds broad applications in the field of biomedicine. Reactivity: The amino functional group in mPEG-NH2 can undergo covalent bonding with other functional groups (such as carboxylic acids, aldehydes, ketones, etc.), enabling specific biological modifications or functionalizations.

2. Applications Drug Modification: mPEG-NH2 is commonly used to modify protein drugs by forming covalent bonds, thereby reducing immunogenicity and improving stability. Biomedical Material Preparation: mPEG-NH2 is also utilized in the preparation of hydrogels, microspheres, and other biomedical materials, involving polymerization, cross-linking, and other chemical reactions. Drug Delivery: In drug delivery systems, mPEG-NH2 serves as a carrier or modifier to enhance drug targeting and bioavailability. Gene Therapy: In gene therapy, mPEG-NH2 is used to modify gene vectors, enhancing their stability and transfection efficiency.

3. Storage Conditions mPEG-NH2 should be stored refrigerated, avoiding repeated freeze-thaw cycles to maintain its stability and activity.

4. Precautions Despite the promising applications of mPEG-NH2 in biomedicine, it is intended for research purposes only and should not be used directly in humans.

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